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Susan Cohen, now at MIT, engineered plant proteins.
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Tackling World Hunger, Molecule by Molecule
If you’ve never done undergraduate research in your life and wonder
if it’s really only glorified busy work, trust the words of one of
UCSB’s five Nobel
Prize winners: “It isn’t just ‘make-work,’” says
Herbert Kroemer, professor of electrical and computer engineering and of
materials, who received the 2000 prize for physics. “Undergraduate
projects arise in the context of bona-fide research. Students’ findings
contribute to solving questions no one has been able to answer before.
In fact, that’s often the most exciting part of the work.”
You can also trust the take of Susan Cohen, who graduated from UCSB with honors in
microbiology. “I enjoyed the undergraduate research
I did because it was challenging,” says Susan. Her research addressed
food-spoilage problems, which are particularly important in the developing
world, where large portions of hard-won harvests are often lost because
of scant refrigeration and poor transportation. Professor Rolf E. Christoffersen
and Susan investigated the mechanism of an enzyme that produces the plant
hormone ethylene, which helps regulate plant development, including fruit
ripening. Professor Christoffersen’s future findings could lead to
new food-storage strategies and dramatically increase the nutritional quality
of food supplies for millions of people.
As part of her inquiry, which focused on the critical amino acid residues
involved when the substrate binds to the enzyme, Susan engineered proteins
by using DNA mutation techniques and computer modeling. Not only was her
research anything but “busy-work,” it produced valuable information
about the plant enzyme Professor Christofferson is investigating.
Finding The Fast Track to Protein Engineering
Susan became interested in biology during high school in Cerritos, California;
as an honors student at UCSB, she enrolled in the Introduction to Research
course through the California Alliance for Minority Participation in Creative
Activities (CAMP) program
for academic credit. Later on, when she wanted experience doing undergraduate
research, she asked the biology department for a list of faculty researchers
and their projects, was intrigued by Professor Christoffersen’s work,
and asked whether she might assist in his lab. He suggested that she send
a brief funding proposal to UCSB’s Office of Undergraduate Research
and Creative activities (URCA).
The result: CAMP awarded her a scholarship amounting to $1,500 for three
academic quarters.

Professor Rolf E. Christoffersen (left) helped Cohen find campus
funding.
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Susan’s undergraduate research is paying off in other ways. She became
one of nine UCSB juniors and seniors who presented their research in a
CAMP undergraduate research symposium at the National Academies of Sciences
and Engineering’s Beckman Conference Center, at UC Irvine.
The UCSB group included mathematics professor Kenneth Millett, CAMP
regional director, and six UCSB freshmen (and potential presenters) who
found information as well as inspiration.
An Investment That Yields Major Dividends
Susan’s research experiences also were a key addition to her graduate-school
applications. The winner of her department’s Bernice M. Sweeney Award
in the Biological Sciences, she was accepted at CalTech, Princeton, and
M.I.T., and is now attending M.I.T. for her doctoral studies in biology. |
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